Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that occurs in the lining of the rectum and colon. Apoptosis of the intestinal epithelial cells (IECs) is common in active UC patients. Ghrelin is reported to be downregulated in apoptosis of IECs induced by tumor necrosis factor-...
Main Authors: | Lin Zhang, Jian Cheng, Jie Shen, Sheng Wang, Chuanyong Guo, Xiaoming Fan |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-03-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2021.661853/full |
Similar Items
-
Circulating Ghrelin Levels and Obestatin/Ghrelin Ratio as a Marker of Activity in Ulcerative Colitis
by: Ja Young Jung, et al.
Published: (2015-01-01) -
Xianglian Pill Suppresses Inflammation and Protects Intestinal Epithelial Barrier by Promoting Autophagy in DSS Induced Ulcerative Colitis Mice
by: Bingyu Wang, et al.
Published: (2021-01-01) -
Influence of Microbiota on Intestinal Immune System in Ulcerative Colitis and Its Intervention
by: Sai-Long Zhang, et al.
Published: (2017-11-01) -
Regulation of Endoplasmic Reticulum Stress-Autophagy: A Potential Therapeutic Target for Ulcerative Colitis
by: Dan Qiao, et al.
Published: (2021-09-01) -
Baitouweng Decoction Ameliorates Ulcerative Colitis in Mice Partially Attributed to Regulating Th17/Treg Balance and Restoring Intestinal Epithelial Barrier
by: Zhiwei Miao, et al.
Published: (2021-01-01)