Expression of hexokinase and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase genes in ERN1 knockdown glioma U87 cells: effect of hypoxia and glutamine or glucose deprivation
Endoplasmic reticulum stress, as well as hypoxia and ischemia, are important factors for tumor neovascularization and growth. Cancer cells preferentially utilize glycolysis in order to satisfy their increased energetic and biosynthetic requirements. High glucose metabolism of cancer cells is caused...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Львівський національний університет імені Івана Франка
2011-12-01
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Series: | Біологічні студії |
Subjects: | |
Online Access: | http://publications.lnu.edu.ua/journals/index.php/biology/article/view/387 |