Expression of hexokinase and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase genes in ERN1 knockdown glioma U87 cells: effect of hypoxia and glutamine or glucose deprivation

Endoplasmic reticulum stress, as well as hypoxia and ischemia, are important factors for tumor neovascularization and growth. Cancer cells preferentially utilize glycolysis in order to satisfy their increased energetic and biosynthetic requirements. High glucose metabolism of cancer cells is caused...

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Bibliographic Details
Main Authors: D. O. Minchenko, R. Y. Marunych, E. V. Khomenko, T. V. Bakalets, O. H. Minchenko
Format: Article
Language:English
Published: Львівський національний університет імені Івана Франка 2011-12-01
Series:Біологічні студії
Subjects:
hk1
hk2
Online Access:http://publications.lnu.edu.ua/journals/index.php/biology/article/view/387