Complete resolution of apparently definite radiological and histological usual interstitial pneumonia

Complete resolution of apparently definite radiological and histological usual interstitial pneumonia

Idiopathic pulmonary fibrosis is considered to be the most common form of pulmonary fibrosis. It is a progressive and irreversible disease with a reported median survival of ~3 years. The pathological correlate is usual interstitial pneumonia (UIP), and although antifibrotic agents can slow down lun...

Full description

Bibliographic Details
Main Authors: D Simon, E Irusen, B Allwood, J Rigby, C Koegelenberg
Format: Article
Language:English
Published: Health and Medical Publishing Group 2018-08-01
Series:South African Medical Journal
Online Access:http://www.samj.org.za/index.php/samj/article/download/12423/8624
id doaj-b405257714334fbebfb1d005ddeac3eb
record_format Article
spelling doaj-b405257714334fbebfb1d005ddeac3eb2020-11-25T01:13:43ZengHealth and Medical Publishing GroupSouth African Medical Journal0256-95742078-51352018-08-01108972672810.7196/SAMJ.2018.v108i9.13335Complete resolution of apparently definite radiological and histological usual interstitial pneumoniaD SimonE IrusenB AllwoodJ RigbyC KoegelenbergIdiopathic pulmonary fibrosis is considered to be the most common form of pulmonary fibrosis. It is a progressive and irreversible disease with a reported median survival of ~3 years. The pathological correlate is usual interstitial pneumonia (UIP), and although antifibrotic agents can slow down lung function decline, they do not completely reverse the disease process. To date, there have been no case reports describing reversal of UIP. We present a case where both the imaging and histology were compatible with definite UIP, yet it reversed with immunosuppressive therapy without the use of antifibrotic agents.http://www.samj.org.za/index.php/samj/article/download/12423/8624
collection DOAJ
language English
format Article
sources DOAJ
author D Simon
E Irusen
B Allwood
J Rigby
C Koegelenberg
spellingShingle D Simon
E Irusen
B Allwood
J Rigby
C Koegelenberg
Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
South African Medical Journal
author_facet D Simon
E Irusen
B Allwood
J Rigby
C Koegelenberg
author_sort D Simon
title Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
title_short Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
title_full Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
title_fullStr Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
title_full_unstemmed Complete resolution of apparently definite radiological and histological usual interstitial pneumonia
title_sort complete resolution of apparently definite radiological and histological usual interstitial pneumonia
publisher Health and Medical Publishing Group
series South African Medical Journal
issn 0256-9574
2078-5135
publishDate 2018-08-01
description Idiopathic pulmonary fibrosis is considered to be the most common form of pulmonary fibrosis. It is a progressive and irreversible disease with a reported median survival of ~3 years. The pathological correlate is usual interstitial pneumonia (UIP), and although antifibrotic agents can slow down lung function decline, they do not completely reverse the disease process. To date, there have been no case reports describing reversal of UIP. We present a case where both the imaging and histology were compatible with definite UIP, yet it reversed with immunosuppressive therapy without the use of antifibrotic agents.
url http://www.samj.org.za/index.php/samj/article/download/12423/8624
work_keys_str_mv AT dsimon completeresolutionofapparentlydefiniteradiologicalandhistologicalusualinterstitialpneumonia
AT eirusen completeresolutionofapparentlydefiniteradiologicalandhistologicalusualinterstitialpneumonia
AT ballwood completeresolutionofapparentlydefiniteradiologicalandhistologicalusualinterstitialpneumonia
AT jrigby completeresolutionofapparentlydefiniteradiologicalandhistologicalusualinterstitialpneumonia
AT ckoegelenberg completeresolutionofapparentlydefiniteradiologicalandhistologicalusualinterstitialpneumonia
_version_ 1725160446762156032

Similar Items