Singlet oxygen induced products of linoleates, 10- and 12-(Z,E)-hydroxyoctadecadienoic acids (HODE), can be potential biomarkers for early detection of type 2 diabetes.

Singlet oxygen induced products of linoleates, 10- and 12-(Z,E)-hydroxyoctadecadienoic acids (HODE), can be potential biomarkers for early detection of type 2 diabetes.

Current diagnostic tests such as glycemic indicators have limitations for early detection of impaired glucose tolerance (IGT), which leads to diabetes. Oxidative stress induced by various oxidants in a random and destructive manner is considered to play an important role in the pathophysiology of a...

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Main Authors: Aya Umeno, Mototada Shichiri, Noriko Ishida, Yoshiko Hashimoto, Kaori Abe, Masatoshi Kataoka, Kohzoh Yoshino, Yoshihisa Hagihara, Nanako Aki, Makoto Funaki, Yasuhiko Asada, Yasukazu Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23691063/pdf/?tool=EBI

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