Inhibition of ABCC6 Transporter Modifies Cytoskeleton and Reduces Motility of HepG2 Cells via Purinergic Pathway

Inhibition of ABCC6 Transporter Modifies Cytoskeleton and Reduces Motility of HepG2 Cells via Purinergic Pathway

ABCC6, belonging to sub-family C of ATP-binding cassette transporter, is an ATP-dependent transporter mainly present in the basolateral plasma membrane of hepatic and kidney cells. Although the substrates transported are still uncertain, ABCC6 has been shown to promote ATP release. The extracellular...

Full description

Bibliographic Details
Main Authors: Angela Ostuni, Monica Carmosino, Rocchina Miglionico, Vittorio Abruzzese, Fabio Martinelli, Daniela Russo, Ilaria Laurenzana, Agata Petillo, Faustino Bisaccia
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
ABCC6
HepG2
probenecid
purinergic pathway
ATP
cytoskeleton
Online Access:https://www.mdpi.com/2073-4409/9/6/1410

Internet

https://www.mdpi.com/2073-4409/9/6/1410

Similar Items