Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice

Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice

Abstract Background Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced CTL responses and improves prevention of tumour growth in animal model...

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Bibliographic Details
Main Authors: Guoying Ni, Zaowen Liao, Shu Chen, Tianfang Wang, Jianwei Yuan, Xuan Pan, Kate Mounsey, Shelley Cavezza, Xiaosong Liu, Ming Q. Wei
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Immunology
Subjects:
Il-10
CD4+ T cells
Intestine
Inflammation
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s12865-017-0224-x

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