Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample

A sample from Bogota's born population (n= 92) was typed at seven PCR - based loci: HLA DQA 1 LDLR, GYPA, HBGG, D758and Gc. The results showed that all loci meet Hardy Weinberg expectations and there is evidence for lack of linkage equilibrium between GYPA y GC loci. The allele frequencies at a...

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Main Author: Grace Terreros Ibáñez
Format: Article
Language:English
Published: Universidad Nacional de Colombia 1999-07-01
Series:Acta Biológica Colombiana
Subjects:
PCR
Online Access:https://revistas.unal.edu.co/index.php/actabiol/article/view/25910
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spelling doaj-b3e4144a75c6412c81fd1425fa2b75212020-11-25T00:54:19ZengUniversidad Nacional de ColombiaActa Biológica Colombiana0120-548X1900-16491999-07-014223017Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sampleGrace Terreros Ibáñez0Universidad Nacional de ColombiaA sample from Bogota's born population (n= 92) was typed at seven PCR - based loci: HLA DQA 1 LDLR, GYPA, HBGG, D758and Gc. The results showed that all loci meet Hardy Weinberg expectations and there is evidence for lack of linkage equilibrium between GYPA y GC loci. The allele frequencies at all PM+ DQA 1 loci differed from African Americans, two loci from Bogota residents and Spanish and four loci from Chileans. The combined power of discrimination for all 6 loci is 0.9997, the combined power of exclusion is 0.8986. The frequency data can be used in forensic analysis and paternity tests to estimate the frequency of a DNA profile in the population of Bogota.https://revistas.unal.edu.co/index.php/actabiol/article/view/25910BogotáPCRLociFrecuencias Alélicas
collection DOAJ
language English
format Article
sources DOAJ
author Grace Terreros Ibáñez
spellingShingle Grace Terreros Ibáñez
Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
Acta Biológica Colombiana
Bogotá
PCR
Loci
Frecuencias Alélicas
author_facet Grace Terreros Ibáñez
author_sort Grace Terreros Ibáñez
title Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
title_short Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
title_full Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
title_fullStr Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
title_full_unstemmed Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
title_sort genetic characterization of the loci hla dqa, ldlr, gypa, hbgg, d7s8 & gc in a bogota born population sample
publisher Universidad Nacional de Colombia
series Acta Biológica Colombiana
issn 0120-548X
1900-1649
publishDate 1999-07-01
description A sample from Bogota's born population (n= 92) was typed at seven PCR - based loci: HLA DQA 1 LDLR, GYPA, HBGG, D758and Gc. The results showed that all loci meet Hardy Weinberg expectations and there is evidence for lack of linkage equilibrium between GYPA y GC loci. The allele frequencies at all PM+ DQA 1 loci differed from African Americans, two loci from Bogota residents and Spanish and four loci from Chileans. The combined power of discrimination for all 6 loci is 0.9997, the combined power of exclusion is 0.8986. The frequency data can be used in forensic analysis and paternity tests to estimate the frequency of a DNA profile in the population of Bogota.
topic Bogotá
PCR
Loci
Frecuencias Alélicas
url https://revistas.unal.edu.co/index.php/actabiol/article/view/25910
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