Genetic characterization of the loci HLA DQA, lDlR, GYPA, HBGG, D7S8 & GC in a Bogota born population sample
A sample from Bogota's born population (n= 92) was typed at seven PCR - based loci: HLA DQA 1 LDLR, GYPA, HBGG, D758and Gc. The results showed that all loci meet Hardy Weinberg expectations and there is evidence for lack of linkage equilibrium between GYPA y GC loci. The allele frequencies at a...
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
1999-07-01
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| Series: | Acta Biológica Colombiana |
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| Online Access: | https://revistas.unal.edu.co/index.php/actabiol/article/view/25910 |
| Summary: | A sample from Bogota's born population (n= 92) was typed at seven PCR - based loci: HLA DQA 1 LDLR, GYPA, HBGG, D758and Gc. The results showed that all loci meet Hardy Weinberg expectations and there is evidence for lack of linkage equilibrium between GYPA y GC loci. The allele frequencies at all PM+ DQA 1 loci differed from African Americans, two loci from Bogota residents and Spanish and four loci from Chileans. The combined power of discrimination for all 6 loci is 0.9997, the combined power of exclusion is 0.8986. The frequency data can be used in forensic analysis and paternity tests to estimate the frequency of a DNA profile in the population of Bogota. |
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| ISSN: | 0120-548X 1900-1649 |