Improved Formulation of <sup>224</sup>Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP

Improved Formulation of <sup>224</sup>Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP

Radium-224-labeled CaCO<sub>3</sub> microparticles have been developed to treat peritoneal carcinomatosis. The microparticles function as carriers of <sup>224</sup>Ra, facilitating intraperitoneal retention of the alpha-emitting radionuclide. It was necessary to control the s...

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Bibliographic Details
Main Authors: Ruth Gong Li, Kim Lindland, Sandra Karen Tonstad, Tina Bjørnlund Bønsdorff, Asta Juzeniene, Sara Westrøm, Roy Hartvig Larsen
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
radiopharmaceutical
radionuclide therapy
alpha therapy
alpha emitter
calcium carbonate
microparticles
Online Access:https://www.mdpi.com/1999-4923/13/5/634

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