The Interplay Between Non-coding RNAs and Insulin-Like Growth Factor Signaling in the Pathogenesis of Neoplasia

The insulin-like growth factors (IGFs) are polypeptides with similar sequences with insulin. These factors regulate cell growth, development, maturation, and aging via different processes including the interplay with MAPK, Akt, and PI3K. IGF signaling participates in the pathogenesis of neoplasia, i...

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Bibliographic Details
Main Authors: Soudeh Ghafouri-Fard, Atefe Abak, Mahdi Mohaqiq, Hamed Shoorei, Mohammad Taheri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IGF
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.634512/full