How to draw the line in biomedical research
The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid t...
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doaj-b3cb598889434a92ac52a04556dfcc7c2021-05-04T21:29:27ZengeLife Sciences Publications LtdeLife2050-084X2013-03-01210.7554/eLife.00638How to draw the line in biomedical researchLisa Huang0Amir Rattner1Han Liu2Jeremy Nathans3Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United StatesDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United StatesDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, United StatesDepartment of Molecular Biology and Genetics, the Department of Neuroscience, the Department of Ophthalmology, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, United StatesThe use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.https://elifesciences.org/articles/00638Tutorialstatisticpublishing |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lisa Huang Amir Rattner Han Liu Jeremy Nathans |
spellingShingle |
Lisa Huang Amir Rattner Han Liu Jeremy Nathans How to draw the line in biomedical research eLife Tutorial statistic publishing |
author_facet |
Lisa Huang Amir Rattner Han Liu Jeremy Nathans |
author_sort |
Lisa Huang |
title |
How to draw the line in biomedical research |
title_short |
How to draw the line in biomedical research |
title_full |
How to draw the line in biomedical research |
title_fullStr |
How to draw the line in biomedical research |
title_full_unstemmed |
How to draw the line in biomedical research |
title_sort |
how to draw the line in biomedical research |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2013-03-01 |
description |
The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot. |
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Tutorial statistic publishing |
url |
https://elifesciences.org/articles/00638 |
work_keys_str_mv |
AT lisahuang howtodrawthelineinbiomedicalresearch AT amirrattner howtodrawthelineinbiomedicalresearch AT hanliu howtodrawthelineinbiomedicalresearch AT jeremynathans howtodrawthelineinbiomedicalresearch |
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