Impaired contextual fear extinction learning is associated with aberrant regulation of CHD-type chromatin remodeling factors

Impaired contextual fear extinction learning is associated with aberrant regulation of CHD-type chromatin remodeling factors

Successful attenuation of fearful memories is a cognitive process requiring initiation of highly coordinated transcription programs. Chromatin-modulating mechanisms such as DNA methylation and histone modifications, including acetylation, are key regulators of these processes. However, knowledge con...

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Bibliographic Details
Main Authors: Alexandra eWille, Verena eMaurer, Paolo ePiatti, Nigel eWhittle, Dietmar eRieder, Nicolas eSingewald, Alexandra eLusser
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Amygdala
epigenetics
gene regulation
nucleosome remodeling
Anxiety behavior
ATP-dependent chromatin remodeling factors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00313/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00313/full

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