Tumor-Associated Macrophage Status in Cancer Treatment

Tumor-Associated Macrophage Status in Cancer Treatment

Tumor-associated macrophages (TAMs) represent the most abundant innate immune cells in tumors. TAMs, exhibiting anti-inflammatory phenotype, are key players in cancer progression, metastasis and resistance to therapy. A high TAM infiltration is generally associated with poor prognosis, but macrophag...

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Bibliographic Details
Main Authors: Anna Maria Malfitano, Simona Pisanti, Fabiana Napolitano, Sarah Di Somma, Rosanna Martinelli, Giuseppe Portella
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
tumor-associated macrophages
chemotherapy
radiotherapy
immune-checkpoint blocking therapy
oncolytic virus
virotherapy
Online Access:https://www.mdpi.com/2072-6694/12/7/1987

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