Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells

Background: Neuroinflammation plays a major role in the development of ischemic stroke, and regulation of the proinflammatory TLR4 signaling pathway in microglia stands to be a promising therapeutic strategy for stroke intervention. Recently, the homeostasis of mitochondrial dynamics has also been r...

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Bibliographic Details
Main Authors: Kecheng Zhou, Jiayu Wu, Jie Chen, Ye Zhou, Xiaolong Chen, Qiaoyun Wu, Yangxinzi Xu, Wenzhan Tu, Xinfa Lou, Guanhu Yang, Songhe Jiang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318302093