Silencing of miR-17-5p suppresses cell proliferation and promotes cell apoptosis by directly targeting PIK3R1 in laryngeal squamous cell carcinoma

Abstract Background Increasing evidence has suggested that microRNAs (miRNAs) act as key post-transcriptional regulators in tumor progression. Previous studies have confirmed that miR-17-5p functions as an oncogene in multiple cancers and contributes to tumor progression. However, the role and biolo...

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Bibliographic Details
Main Authors: Jian-Xing Wang, Xin-Ju Jia, Yan Liu, Jin-Hui Dong, Xiu-Min Ren, Ou Xu, Sheng-Hui Liu, Chun-Guang Shan
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-1096-3

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