Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies

Gynecologic cancers cause over 600,000 deaths annually in women worldwide. The development of chemoresistance after initial rounds of chemotherapy contributes to tumor relapse and death due to gynecologic malignancies. In this regard, cancer stem cells (CSCs), a subpopulation of stem cells with the...

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Bibliographic Details
Main Authors: Vaishnavi Muralikrishnan, Thomas D. Hurley, Kenneth P. Nephew
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/4/961