Synthesis, physical-chemical properties and research of acute toxicity of 1,2,4-triazole derivatives containing thiophene core
The aim of research. Modern drugs must have certain characteristics, such as low toxicity and high efficiency. Special attention should be given to esthers of 2-(1,2,4-triazoles-3-iltio)acetic acids. It has been found that compounds of this class are able to show analgesic, neuroleptic, diuretic, an...
Main Author: | V. A. Salionov |
---|---|
Format: | Article |
Language: | English |
Published: |
Zaporozhye State Medical University
2015-12-01
|
Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
Subjects: | |
Online Access: | http://pharmed.zsmu.edu.ua/article/view/52616/49791 |
Similar Items
-
The search of new biologically active compounds with antibacterial and antifungal activity among 1,2,4-triazole-3-thiol derivatives with the remnants of thiophene
by: V. O. Salionov, et al.
Published: (2017-08-01) -
Acute toxicity of S-derivatives of 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles
by: O. A. Suhak, et al.
Published: (2017-12-01) -
Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
by: A. A. Safonov
Published: (2018-08-01) -
The research of acute toxicity of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol derivatives
by: I. I. Аksyonova-Seliuk, et al.
Published: (2017-08-01) -
Actoprotective activity of some 5-(thiophen-3-ylmethyl)-4-R1-1,2,4-triazole-3-thiols derivatives
by: O. A. Bihdan
Published: (2020-07-01)