The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line

The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line

Adenosine receptor family especially A1 type is expressed in breast cancer cells in which P53 and caspase genes are wild-type. The aim of this study was to investigate the correlation between A1 receptor and either cell apoptosis or proliferation and also to recognize the relationship between this r...

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Bibliographic Details
Main Authors: Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudieh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Caspase; Adenosine A1; Apoptosis; Genes; p53; MCF-7 cells
Online Access:http://www.jrps.ir/article.asp?issn=1735-5362;year=2016;volume=11;issue=4;spage=303;epage=310;aulast=Dastjerdi

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