PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting.
Plant-pathogenic Xanthomonas bacteria secrete transcription activator-like effectors (TALEs) into host cells, where they act as transcriptional activators on plant target genes to support bacterial virulence. TALEs have a unique modular DNA-binding domain composed of tandem repeats. Two amino acids...
Main Authors: | Annett Erkes, Stefanie Mücke, Maik Reschke, Jens Boch, Jan Grau |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-07-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007206 |
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