Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1.

Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1.

Tubulo-interstitial fibrosis is a common, destructive endpoint for a variety of kidney diseases. Fibrosis is well correlated with the loss of kidney function in both humans and rodents. The identification of modulators of fibrosis could provide novel therapeutic approaches to reducing disease progre...

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Bibliographic Details
Main Authors: Zhong-Jian Shen, Jie Hu, Kazuhiro Shiizaki, Makoto Kuro-o, James S Malter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4767802?pdf=render

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