Study design of the DAS-OLT trial: a randomized controlled trial to evaluate the impact of dexmedetomidine on early allograft dysfunction following liver transplantation

Study design of the DAS-OLT trial: a randomized controlled trial to evaluate the impact of dexmedetomidine on early allograft dysfunction following liver transplantation

Abstract Background Perioperative ischemia/reperfusion (I/R) injury during liver transplantation is strongly associated with early allograft dysfunction (EAD), graft loss, and mortality. Hepatic I/R injury also causes remote damage to other organs including the renal and pulmonary systems. Dexmedeto...

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Bibliographic Details
Main Authors: Chenlu Ni, Joe Masters, Ling Zhu, Weifeng Yu, Yingfu Jiao, Yuting Yang, Cui Cui, Suqing Yin, Liqun Yang, Bo Qi, Daqing Ma
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Trials
Subjects:
Liver transplantation
Dexmedetomidine
Early allograft dysfunction
Primary graft dysfunction
Online Access:http://link.springer.com/article/10.1186/s13063-020-04497-7

Internet

http://link.springer.com/article/10.1186/s13063-020-04497-7

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