Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis

Identification of Hub Genes Associated With Sensitivity of 5-Fluorouracil Based Chemotherapy for Colorectal Cancer by Integrated Bioinformatics Analysis

Colorectal cancer (CRC) is one of the most common malignant tumors. 5-fluorouracil (5-FU) has been used for the standard first-line treatment for CRC patients for several decades. Although 5-FU based chemotherapy has increased overall survival (OS) of CRC patients, the resistance of CRC to 5-FU base...

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Bibliographic Details
Main Authors: Ya Wang, Qunhui Wei, Yuqiao Chen, Shichao Long, Yuanbing Yao, Kai Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
5-fluorouracil
chemotherapy sensitive
weighted gene co-expression network analysis
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.604315/full

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