THE PROBLEM OF DIAGNOSING VITAMIN B12 DEFICIENCY

Vitamin B12 deficiency (cobalamin) is a common cause of megaloblastic anemia, with various neuropsychiatric symptoms. The prevalence is not known with certainty, but the incidence seems to increase with age. The diagnosis is usually based on the identification of a low serum level of vitamin B12 wi...

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Bibliographic Details
Main Authors: Ana Maria Alexandra Stănescu, Dumitru Matei, Daniela Miricescu, Daniela Oana Toader, Florica Şandru, Constantin Ștefani, Alexandra Totan, Camelia Cristina Diaconu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2019-12-01
Series:Romanian Medical Journal
Subjects:
Online Access:https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.4/RMJ_2019_4_Art-06.pdf
Description
Summary:Vitamin B12 deficiency (cobalamin) is a common cause of megaloblastic anemia, with various neuropsychiatric symptoms. The prevalence is not known with certainty, but the incidence seems to increase with age. The diagnosis is usually based on the identification of a low serum level of vitamin B12 with clinical evidence of deficiency and with a good response to vitamin B12 replacement therapy. When confirming the diagnosis, consideration should be given to the etiology that may be due to nutritional deficiency, malabsorption and other gastrointestinal causes.
ISSN:1220-5478
2069-606X