Stem cell-secreted 14,15- epoxyeicosatrienoic acid rescues cholesterol homeostasis and autophagic flux in Niemann–Pick-type C disease

Stem cell-secreted 14,15- epoxyeicosatrienoic acid rescues cholesterol homeostasis and autophagic flux in Niemann–Pick-type C disease

Inherited metabolic disease: Restoring motor function by reducing cholesterol An acid secreted by stem cells can reduce the excess cholesterol caused by a genetic metabolic disorder. Niemann–Pick type C disease is a rare, inherited condition that causes defective muscular development and progressive...

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Bibliographic Details
Main Authors:	Insung Kang, Byung-Chul Lee, Jin Young Lee, Jae-Jun Kim, Eun-Ah Sung, Seung Eun Lee, Nari Shin, Soon Won Choi, Yoojin Seo, Hyung-Sik Kim, Kyung-Sun Kang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-11-01
Series:	Experimental and Molecular Medicine
Online Access:	https://doi.org/10.1038/s12276-018-0176-0

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