Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis

Abstract Objective Surgical resection plays an essential role in the treatment of Pulmonary Tuberculosis (PTB). There are few reports comparing lobectomy and sublobectomy for pulmonary TB with cavity. To compare the advantages between lobectomy and sublobectomy for localized cavitory PTB, we perform...

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Main Authors: Yong Yang, Shaojun Zhang, Zhengwei Dong, Yong Xu, Xuefei Hu, Gening Jiang, Lin Fan, Liang Duan
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-021-01401-5
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spelling doaj-b37671fa420143f2ae45159181d1625b2021-03-21T12:08:17ZengBMCJournal of Cardiothoracic Surgery1749-80902021-03-011611710.1186/s13019-021-01401-5Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosisYong Yang0Shaojun Zhang1Zhengwei Dong2Yong Xu3Xuefei Hu4Gening Jiang5Lin Fan6Liang Duan7Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of MedicineClinic and Research Center of Tuberculosis, Shanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of MedicineDepartment of Pathology, Shanghai Pulmonary Hospital, Tongji University School of MedicineDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of MedicineDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of MedicineDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of MedicineClinic and Research Center of Tuberculosis, Shanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of MedicineDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of MedicineAbstract Objective Surgical resection plays an essential role in the treatment of Pulmonary Tuberculosis (PTB). There are few reports comparing lobectomy and sublobectomy for pulmonary TB with cavity. To compare the advantages between lobectomy and sublobectomy for localized cavitory PTB, we performed a single-institution cross sectional cohort study of the surgical patients. Methods We consecutively included 203 patients undergoing lobectomy or sublobectomy surgery for localized cavitary PTB. All patients were followed up, recorded and compared their surgical complication, outcome and associated characteristics. Results Both groups had similar outcomes after follow up for 13.1 ± 12.1 months, however, sublobectomy group suffered fewer intraoperative blood losses, shorter length of stay, and fewer operative complications than lobectomy group (P <  0.05). Both groups obtained satisfactory outcome with postoperatively medicated for similar period of time and few relapse (P > 0.05). Conclusion Both sublobectomy and lobectomy resection were effective ways for cavitary PTB with surgical indications. If adequate anti-TB chemotherapy had been guaranteed, sublobectomy is able to be recommended due to more lung parenchyma retain, faster recover, and fewer postoperative complications.https://doi.org/10.1186/s13019-021-01401-5Pulmonary tuberculosisCavityLobectomySublobectomyComplicationPrognosis
collection DOAJ
language English
format Article
sources DOAJ
author Yong Yang
Shaojun Zhang
Zhengwei Dong
Yong Xu
Xuefei Hu
Gening Jiang
Lin Fan
Liang Duan
spellingShingle Yong Yang
Shaojun Zhang
Zhengwei Dong
Yong Xu
Xuefei Hu
Gening Jiang
Lin Fan
Liang Duan
Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
Journal of Cardiothoracic Surgery
Pulmonary tuberculosis
Cavity
Lobectomy
Sublobectomy
Complication
Prognosis
author_facet Yong Yang
Shaojun Zhang
Zhengwei Dong
Yong Xu
Xuefei Hu
Gening Jiang
Lin Fan
Liang Duan
author_sort Yong Yang
title Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
title_short Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
title_full Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
title_fullStr Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
title_full_unstemmed Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
title_sort sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
publisher BMC
series Journal of Cardiothoracic Surgery
issn 1749-8090
publishDate 2021-03-01
description Abstract Objective Surgical resection plays an essential role in the treatment of Pulmonary Tuberculosis (PTB). There are few reports comparing lobectomy and sublobectomy for pulmonary TB with cavity. To compare the advantages between lobectomy and sublobectomy for localized cavitory PTB, we performed a single-institution cross sectional cohort study of the surgical patients. Methods We consecutively included 203 patients undergoing lobectomy or sublobectomy surgery for localized cavitary PTB. All patients were followed up, recorded and compared their surgical complication, outcome and associated characteristics. Results Both groups had similar outcomes after follow up for 13.1 ± 12.1 months, however, sublobectomy group suffered fewer intraoperative blood losses, shorter length of stay, and fewer operative complications than lobectomy group (P <  0.05). Both groups obtained satisfactory outcome with postoperatively medicated for similar period of time and few relapse (P > 0.05). Conclusion Both sublobectomy and lobectomy resection were effective ways for cavitary PTB with surgical indications. If adequate anti-TB chemotherapy had been guaranteed, sublobectomy is able to be recommended due to more lung parenchyma retain, faster recover, and fewer postoperative complications.
topic Pulmonary tuberculosis
Cavity
Lobectomy
Sublobectomy
Complication
Prognosis
url https://doi.org/10.1186/s13019-021-01401-5
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AT zhengweidong sublobectomyisasafealternativeforlocalizedcavitarypulmonarytuberculosis
AT yongxu sublobectomyisasafealternativeforlocalizedcavitarypulmonarytuberculosis
AT xuefeihu sublobectomyisasafealternativeforlocalizedcavitarypulmonarytuberculosis
AT geningjiang sublobectomyisasafealternativeforlocalizedcavitarypulmonarytuberculosis
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