Neuroprotective γ-Pyrones from <i>Fusarium Solani</i> JS-0169: Cell-Based Identification of Active Compounds and an Informatics Approach to Predict the Mechanism of Action

Neuroprotective γ-Pyrones from <i>Fusarium Solani</i> JS-0169: Cell-Based Identification of Active Compounds and an Informatics Approach to Predict the Mechanism of Action

Glutamate toxicity has been implicated in neuronal cell death in both acute CNS injury and in chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, <i>Fusarium solani</i> JS-0169 isolated from the l...

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Bibliographic Details
Main Authors: Hyun Gyu Choi, Ji Hoon Song, Musun Park, Soonok Kim, Chang-Eop Kim, Ki Sung Kang, Sang Hee Shim
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomolecules
Subjects:
neuroprotection
<i>fusarium solani</i>
endophyte
γ-pyrones
informatics approach
Online Access:https://www.mdpi.com/2218-273X/10/1/91

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