Automated tumor proportion score analysis for PD-L1 (22C3) expression in lung squamous cell carcinoma

Abstract Programmed cell death ligend-1 (PD-L1) expression by immunohistochemistry (IHC) assays is a predictive marker of anti-PD-1/PD-L1 therapy response. With the popularity of anti-PD-1/PD-L1 inhibitor drugs, quantitative assessment of PD-L1 expression becomes a new labor for pathologists. Manual...

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Bibliographic Details
Main Authors: Jingxin Liu, Qiang Zheng, Xiao Mu, Yanfei Zuo, Bo Xu, Yan Jin, Yue Wang, Hua Tian, Yongguo Yang, Qianqian Xue, Ziling Huang, Lijun Chen, Bin Gu, Xianxu Hou, Linlin Shen, Yan Guo, Yuan Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95372-1