Development and validation of a rapid and sensitive UHPLC–MS/MS method for the determination of paliperidone in beagle dog plasma

Development and validation of a rapid and sensitive UHPLC–MS/MS method for the determination of paliperidone in beagle dog plasma

In order to evaluate the pharmacokinetic profile of paliperidone extended-release tablets in vivo, a simple and rapid ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method was developed and validated for the determination of paliperidone in beagle dog plasma. Pal...

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Bibliographic Details
Main Authors:	Hongming Chen, Longshan Zhao, Guangjing Li, Donglei Leng, Panqin Ma, Lijin Tong, Tianhong Zhang
Format:	Article
Language:	English
Published:	Elsevier 2014-10-01
Series:	Asian Journal of Pharmaceutical Sciences
Subjects:	Paliperidone Dog plasma UHPLC–MS/MS Pharmacokinetics
Online Access:	http://www.sciencedirect.com/science/article/pii/S181808761400066X

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