Tumor-suppressor miRNA-27b-5p regulates the growth and metastatic behaviors of ovarian carcinoma cells by targeting CXCL1

Tumor-suppressor miRNA-27b-5p regulates the growth and metastatic behaviors of ovarian carcinoma cells by targeting CXCL1

Abstract Background MicroRNAs (miRNAs) play crucial functions in the progression of ovarian cancer. MicroRNA-27b-5p (miR-27b-5p) has been identified as a cancer-associated miRNA. Nevertheless, the expression profile of miR-27b-5p and its functions in ovarian cancer are unexplored. Methods qRT-PCR an...

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Bibliographic Details
Main Authors: Chun Hua Liu, Xue Ning Jing, Xiao Lan Liu, Shan Yong Qin, Min Wei Liu, Chun Hong Hou
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
MiR-27b-5p
Migration
Invasion
CXCL1
Online Access:http://link.springer.com/article/10.1186/s13048-020-00697-6

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