Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site

Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site

Abstract Background Therapeutic vaccines against cervical cancer remain ineffective. Previously, we demonstrated that blocking the signalling of a cytokine, interleukin 10, at the time of immunisation elicited significantly higher numbers of antigen specific T cells and inhibited tumour growth in mi...

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Bibliographic Details
Main Authors: Xuan Pan, Bowei Ma, Xinchao You, Shu Chen, Jialing Wu, Tianfang Wang, Shelley F. Walton, Jianwei Yuan, Xiaolian Wu, Guoqiang Chen, Yuejian Wang, Guoying Ni, Xiaosong Liu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Caerin peptide
Therapeutic vaccine
Cervical cancer
Tumour microenvironment
Online Access:http://link.springer.com/article/10.1186/s12906-019-2571-z

Internet

http://link.springer.com/article/10.1186/s12906-019-2571-z

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