Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia

Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preve...

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Main Authors: Yoshio Shimizu, Keiichi Wakabayashi, Ayako Totsuka, Yoko Hayashi, Shusaku Nitta, Kazuaki Hara, Maiko Akira, Yasuhiko Tomino, Yusuke Suzuki
Format: Article
Language:English
Published: Karger Publishers 2019-07-01
Series:Case Reports in Nephrology and Dialysis
Subjects:
Online Access:https://www.karger.com/Article/FullText/501877
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spelling doaj-b341c261eb924084859adf53bdcc75b52020-11-25T01:32:32ZengKarger PublishersCase Reports in Nephrology and Dialysis2296-97052019-07-01929210110.1159/000501877501877Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal HypouricemiaYoshio ShimizuKeiichi WakabayashiAyako TotsukaYoko HayashiShusaku NittaKazuaki HaraMaiko AkiraYasuhiko TominoYusuke SuzukiHereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training.https://www.karger.com/Article/FullText/501877ExerciseAcute kidney injuryHereditary renal hypouricemiaPolice officer
collection DOAJ
language English
format Article
sources DOAJ
author Yoshio Shimizu
Keiichi Wakabayashi
Ayako Totsuka
Yoko Hayashi
Shusaku Nitta
Kazuaki Hara
Maiko Akira
Yasuhiko Tomino
Yusuke Suzuki
spellingShingle Yoshio Shimizu
Keiichi Wakabayashi
Ayako Totsuka
Yoko Hayashi
Shusaku Nitta
Kazuaki Hara
Maiko Akira
Yasuhiko Tomino
Yusuke Suzuki
Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
Case Reports in Nephrology and Dialysis
Exercise
Acute kidney injury
Hereditary renal hypouricemia
Police officer
author_facet Yoshio Shimizu
Keiichi Wakabayashi
Ayako Totsuka
Yoko Hayashi
Shusaku Nitta
Kazuaki Hara
Maiko Akira
Yasuhiko Tomino
Yusuke Suzuki
author_sort Yoshio Shimizu
title Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_short Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_full Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_fullStr Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_full_unstemmed Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_sort exercise-induced acute kidney injury in a police officer with hereditary renal hypouricemia
publisher Karger Publishers
series Case Reports in Nephrology and Dialysis
issn 2296-9705
publishDate 2019-07-01
description Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training.
topic Exercise
Acute kidney injury
Hereditary renal hypouricemia
Police officer
url https://www.karger.com/Article/FullText/501877
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