Intermolecular Interactions in Crystal Structures of Imatinib-Containing Compounds

Imatinib, one of the most used therapeutic agents to treat leukemia, is an inhibitor that specifically blocks the activity of tyrosine kinases. The molecule of imatinib is flexible and contains several functional groups able to take part in H-bonding and hydrophobic interactions. Analysis of molecul...

Full description

Bibliographic Details
Main Authors: Anna V. Vologzhanina, Ivan E. Ushakov, Alexander A. Korlyukov
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
API
Online Access:https://www.mdpi.com/1422-0067/21/23/8970