Parametric Estimation of Reference Signal Intensity for Semi-Quantification of Tau Deposition: A Flortaucipir and [18F]-APN-1607 Study

Parametric Estimation of Reference Signal Intensity for Semi-Quantification of Tau Deposition: A Flortaucipir and [18F]-APN-1607 Study

BackgroundTau positron emission tomography (PET) imaging can reveal the pathophysiology and neurodegeneration that occurs in Alzheimer’s disease (AD) in vivo. The standardized uptake value ratio (SUVR) is widely used for semi-quantification of tau deposition but is susceptible to disturbance from th...

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Bibliographic Details
Main Authors: Huiwei Zhang, Min Wang, Jiaying Lu, Weiqi Bao, Ling Li, Jiehui Jiang, Chuantao Zuo, and Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neuroscience
Subjects:
APN-1607
flortaucipir
tau
neurodegeneration
Alzheimer’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.598234/full

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