Lipopolysaccharide Preparation Derived From Porphyromonas gingivalis Induces a Weaker Immuno-Inflammatory Response in BV-2 Microglial Cells Than Escherichia coli by Differentially Activating TLR2/4-Mediated NF-κB/STAT3 Signaling Pathways

Lipopolysaccharide Preparation Derived From Porphyromonas gingivalis Induces a Weaker Immuno-Inflammatory Response in BV-2 Microglial Cells Than Escherichia coli by Differentially Activating TLR2/4-Mediated NF-κB/STAT3 Signaling Pathways

Alzheimer’s disease (AD) is a degenerative disease of the central nervous system with unclear etiology and pathogenesis. In recent years, as the infectious theory and endotoxin hypothesis of AD has gained substantial attention, several studies have proposed that Porphyromonas gingivalis (P. gingival...

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Bibliographic Details
Main Authors: Che Qiu, Zhen Yuan, Zhiyan He, Huiwen Chen, Yue Liao, Shiliang Li, Wei Zhou, Zhongchen Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Porphyromonas gingivalis
lipopolysaccharide
BV-2 microglial cells
immuno-inflammatory
TLRs
NF-κB signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.606986/full

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