A Study and Application of Biocatalytic Synthesis of (S)-N-Boc-3-hydroxypiperidine

This paper first uses the environmental friendly whole cell of biocatalyst pichia pastoris SIT2014 to asymmetrically synthesized anti-tumor drug of chiral intermediate (S)-N-Boc-3-hydroxypiperidine.. Improve the final biocatalytic reduction yield to 85.4% based on the study of fermentation optimizat...

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Bibliographic Details
Main Authors: Chen Ying, Xu Yi, Chen Jianbo
Format: Article
Language:English
Published: EDP Sciences 2015-01-01
Series:MATEC Web of Conferences
Subjects:
Online Access:http://dx.doi.org/10.1051/matecconf/20152205020