A Study and Application of Biocatalytic Synthesis of (S)-N-Boc-3-hydroxypiperidine
This paper first uses the environmental friendly whole cell of biocatalyst pichia pastoris SIT2014 to asymmetrically synthesized anti-tumor drug of chiral intermediate (S)-N-Boc-3-hydroxypiperidine.. Improve the final biocatalytic reduction yield to 85.4% based on the study of fermentation optimizat...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
EDP Sciences
2015-01-01
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Series: | MATEC Web of Conferences |
Subjects: | |
Online Access: | http://dx.doi.org/10.1051/matecconf/20152205020 |