Detection of Gene Promoter Methylation and Protein Expression of p21 in Psoriasis

Detection of Gene Promoter Methylation and Protein Expression of p21 in Psoriasis

Abstract. Object:. The study was aimed to detect the methylation patterns in psoriasis tissues. Methods:. We collected 15 psoriasis tissues and 19 uninvolved psoriatic samples from psoriasis patients, and 3 normal skin samples from healthy control, and investigated the methylation levels of p21 gene...

Full description

Bibliographic Details
Main Authors:	Xin-Mei Liu, Dong Luo, Hui-Qin Wang, Jing-Zhan Zhang, Xiao-Jing Kang, Wei-Dong Wu
Format:	Article
Language:	English
Published:	Wolters Kluwer Health 2019-12-01
Series:	International Journal of Dermatology and Venerology
Online Access:	http://journals.lww.com/10.1097/JD9.0000000000000051

Similar Items

Effects of HBV X protein on expression and promoter methylation of p16 tumor suppressor gene
by: KANG Yanhong, et al.
Published: (2016-03-01)

Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21
by: Cheng Wu, et al.
Published: (2020-06-01)

LMNB2 promotes the progression of colorectal cancer by silencing p21 expression
by: Chen-Hua Dong, et al.
Published: (2021-03-01)

Identification of Potential Biomarkers for Psoriasis by DNA Methylation and Gene Expression Datasets
by: Yong Liu, et al.
Published: (2021-08-01)

Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women
by: Mahdiyeh Harati-Sadegh, et al.
Published: (2019-11-01)

Expression of p16 in psoriasis and chronic spongiotic dermatitis
by: Viktoryia Kazlouskaya, et al.
Published: (2015-01-01)

CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity
by: Zhao-Ru Dong, et al.
Published: (2021-05-01)

Promoter methylation of IGFBP-3 and p53 expression in ovarian endometrioid carcinoma
by: Huang Su-Cheng, et al.
Published: (2009-12-01)

Psoriasis, biologic therapy, and the pandemic of the 21st century
by: Miguel Nogueira, et al.
Published: (2020-05-01)

GSK-3β Regulates the Expression of P21 to Promote the Progression of Chordoma
by: Chen L, et al.
Published: (2021-01-01)

LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint
by: Sarma, Kavitha, et al.
Published: (2017)

Plasma MicroRNA Expression Profiles in Psoriasis
by: Shiju Xiao, et al.
Published: (2020-01-01)

LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8
by: Hai-Yan Jia, et al.
Published: (2019-10-01)

Identification of candidate biomarkers and pathways associated with psoriasis using bioinformatics analysis
by: Yongqi Luo, et al.
Published: (2020-07-01)

Expression of apoptosis regulating proteins p53 and bcl-2 in psoriasis
by: Nikhil Moorchung, et al.
Published: (2015-01-01)

Methylation of p15INK4b and expression of ANRIL on chromosome 9p21 are associated with coronary artery disease.
by: Jianhui Zhuang, et al.
Published: (2012-01-01)

DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes.
by: Kristina Gervin, et al.
Published: (2012-01-01)

Histone Lysine Methylation in TGF-β1 Mediated p21 Gene Expression in Rat Mesangial Cells
by: Qiaoyan Guo, et al.
Published: (2016-01-01)

Eucommia ulmoides Oliv. (Du-Zhong) Lignans Inhibit Angiotensin II-Stimulated Proliferation by Affecting P21, P27, and Bax Expression in Rat Mesangial Cells
by: Xian Jing, et al.
Published: (2015-01-01)

Teratogenicity of Arecoline Hydrobromide in Developing Embryos and Its Effects on p53, p21 and cyclin D1 Expression
by: Liao Mei-Hui, et al.
Published: (2002)

MiR-17 and miR-93 Promote Tumor Progression by Targeting p21 in Patients with Chordoma
by: Dong W, et al.
Published: (2021-05-01)

LncRNA UCA1 promotes renal cell carcinoma proliferation through epigenetically repressing p21 expression and negatively regulating miR-495
by: Yun Lu, et al.
Published: (2017-04-01)

Beta-catenin expression in psoriasis
by: Mohamed Abd El-wahed Gaber, et al.
Published: (2015-01-01)

Hepcidin expression in psoriasis patients
by: Nursel Dilek, et al.
Published: (2014-01-01)

Association between P16INK4a promoter methylation and HNSCC: a meta-analysis of 21 published studies.
by: Hao Shi, et al.
Published: (2015-01-01)

Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells
by: Geng Y, et al.
Published: (2018-08-01)

Spreading of Alu methylation to the promoter of the MLH1 gene in gastrointestinal cancer.
by: Xiyin Wang, et al.
Published: (2011-01-01)

Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma
by: Fu Jia, et al.
Published: (2009-12-01)

Effectiveness and safety of different doses of pioglitazone in psoriasis: a meta-analysis of randomized controlled trials
by: Jing-Zhan Zhang, et al.
Published: (2020-02-01)

Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis
by: Aditi Chandra, et al.
Published: (2018-08-01)

Immunohistochemical expression of P53, Ki-67, and CD34 in psoriasis and psoriasiform dermatitis
by: Ramezani Mazaher, et al.
Published: (2019-12-01)

The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?
by: Hui Liu, et al.
Published: (2021-03-01)

Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis.
by: Hu Lei, et al.
Published: (2017-01-01)

Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis
by: Panpan Liu, et al.
Published: (2021-03-01)

Expression of Angiogenic Factors in Psoriasis Vulgaris
by: Lakshna Sankar, et al.
Published: (2017-03-01)

Immunohistochemical Expression of Caspase-3 in Psoriasis
by: Shaimaa M.M. Bebars, et al.
Published: (2017-07-01)

Aberrations in Lipid Expression and Metabolism in Psoriasis
by: Julia Nowowiejska, et al.
Published: (2021-06-01)

MNX1 Promotes Malignant Progression of Cervical Cancer via Repressing the Transcription of p21cip1
by: Biqing Zhu, et al.
Published: (2020-08-01)

p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes
by: Wen He, et al.
Published: (2017-06-01)

Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression
by: Tao Luo, et al.
Published: (2020-12-01)