DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS

Objective: To analyze the distribution features of Gleason score in the different prostate zones. Material & Method: Twenty paraffin block specimens of radical prostatectomy were analyzed looking for Gleason score distribution in each zone. Specimens were stained with Hematoxilin Eosin. Results:...

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Bibliographic Details
Main Authors: Indra Jaya, Suwandi Sugandi, Anglita Yantisetiasti, Betthy S. S. Hernowo
Format: Article
Language:English
Published: IKATAN AHLI UROLOGI INDONESIA 2014-11-01
Series:Jurnal Urologi Indonesia
Online Access:https://juri.urologi.or.id/juri/article/view/50
Description
Summary:Objective: To analyze the distribution features of Gleason score in the different prostate zones. Material & Method: Twenty paraffin block specimens of radical prostatectomy were analyzed looking for Gleason score distribution in each zone. Specimens were stained with Hematoxilin Eosin. Results: Among the 20 cancers, 16 (80%) specimens had more than one focus. Most foci were found in peripheral zone (95%), only one specimen contained foci solely found in transitional zone. More than half (55%) prostate specimens contain three different Gleason grades. Only one specimen contained a single grade. Conclusion: Our results confirm the heterogeneous, multifocal, and multizonal nature of prostate carcinomas. Most specimens had more than one tumor focus, with predominant location in the peripheral zone. Almost all transition zone foci were found concomitantly with peripheral zone foci. Keywords: Prostate cancer, prostate zones, Gleason score.
ISSN:0853-442X
2355-1402