Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity
Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity. The pathogenic mechanism of neurotoxicity is not clear, possibly MTX-associated b...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Society of Medical Biochemists of Serbia, Belgrade
2009-01-01
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Series: | Journal of Medical Biochemistry |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2009/1452-82580901011V.pdf |