Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity

Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity. The pathogenic mechanism of neurotoxicity is not clear, possibly MTX-associated b...

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Bibliographic Details
Main Authors: Vezmar Sandra, Bode Udo, Jaehde Ulrich
Format: Article
Language:English
Published: Society of Medical Biochemists of Serbia, Belgrade 2009-01-01
Series:Journal of Medical Biochemistry
Subjects:
csf
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2009/1452-82580901011V.pdf