CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS

Miliary tuberculosis (TB) is due to hematogenous spread of Mycobacterium tuberculosis. Clinical manifestations are nonspecific and protean, depending on the predominant site of involvement.We evaluated the clinical manifestations of 15 patients with miliary TB. The diagnosis of miliary tuberculosis...

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Main Author: J. Ayatollahi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2004-12-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2767
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spelling doaj-b2f62070d87f413a9bec11269da1e8692020-11-25T03:22:53ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942004-12-01426CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS J. Ayatollahi0 Miliary tuberculosis (TB) is due to hematogenous spread of Mycobacterium tuberculosis. Clinical manifestations are nonspecific and protean, depending on the predominant site of involvement.We evaluated the clinical manifestations of 15 patients with miliary TB. The diagnosis of miliary tuberculosis was based on the identification of miliary nodules on chest radiography and one of the three following criteria: 1) positive acid-fast bacilli smear and/or culture (14/15), 2) histopathological identification of TB histopathological granuloma (4/15), or 3) radiological and clinical improvement after anti-tuberculosis treatment (14/15). The median age (±SD) of the patients was 52.6±19.1 years. Only one patient had underlying diseases, diabetes mellitus. Three patients developed acute respiratory distress syndrome (ARDS), one of whom died during intensive care. ARDS caused by miliary TB is associated with a high fatality rate, scope remains for improvement in its management.https://acta.tums.ac.ir/index.php/acta/article/view/2767Miliary tuberculosisARDSMycobacterium tuberculosis
collection DOAJ
language English
format Article
sources DOAJ
author J. Ayatollahi
spellingShingle J. Ayatollahi
CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
Acta Medica Iranica
Miliary tuberculosis
ARDS
Mycobacterium tuberculosis
author_facet J. Ayatollahi
author_sort J. Ayatollahi
title CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
title_short CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
title_full CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
title_fullStr CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
title_full_unstemmed CLINICAL MANIFESTATIONS AND OUTCOME OF MILIARY TUBERCULOSIS
title_sort clinical manifestations and outcome of miliary tuberculosis
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 2004-12-01
description Miliary tuberculosis (TB) is due to hematogenous spread of Mycobacterium tuberculosis. Clinical manifestations are nonspecific and protean, depending on the predominant site of involvement.We evaluated the clinical manifestations of 15 patients with miliary TB. The diagnosis of miliary tuberculosis was based on the identification of miliary nodules on chest radiography and one of the three following criteria: 1) positive acid-fast bacilli smear and/or culture (14/15), 2) histopathological identification of TB histopathological granuloma (4/15), or 3) radiological and clinical improvement after anti-tuberculosis treatment (14/15). The median age (±SD) of the patients was 52.6±19.1 years. Only one patient had underlying diseases, diabetes mellitus. Three patients developed acute respiratory distress syndrome (ARDS), one of whom died during intensive care. ARDS caused by miliary TB is associated with a high fatality rate, scope remains for improvement in its management.
topic Miliary tuberculosis
ARDS
Mycobacterium tuberculosis
url https://acta.tums.ac.ir/index.php/acta/article/view/2767
work_keys_str_mv AT jayatollahi clinicalmanifestationsandoutcomeofmiliarytuberculosis
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