Validation of Remote Dielectric Sensing (ReDS) in Monitoring Adult Patients Affected by COVID-19 Pneumonia

• Main Authors: Federico Mei, Alessandro Di Marco Berardino, Martina Bonifazi, Lara Letizia Latini, Lina Zuccatosta, Stefano Gasparini
• Format: Article
• Language: English
• Published: MDPI AG 2021-05-01
• Series: Diagnostics
• Subjects: COVID-19 pneumonia; lung edema; fluid monitoring; computed tomography; remote dielectric sensing
• Online Access: https://www.mdpi.com/2075-4418/11/6/1003

Remote dielectric sensing (ReDS) is a non-invasive electromagnetic wave technology which provides an accurate reading of lung fluid content, and it has been reported as a valid tool in monitoring heart failure patients. Considering that morphological alterations in COVID-19 include pulmonary edema, the purpose of the present study was to evaluate the reliability of ReDS technology in assessing the excess of lung fluid status in COVID-19 pneumonia, as compared to CT scans. In this pilot single center study, confirmed COVID-19 patients were enrolled on admission to an intermediate care unit. Measurements with the ReDS system and CT scans were performed on admission and at weeks 1 and 2. Eleven patients were recruited. The average change in ReDS was −3.1 ± 1.7 after one week (<i>p</i> = 0.001) and −4.6 ± 2.9 after two weeks (<i>p</i> = 0.006). A similar trend was seen in total CT score (−3.3 ± 2.1, <i>p</i> = 0.001). The level of agreement between ReDS and CT changes yielded a perfect result. Statistically significant changes were observed in lactate dehydrogenase, lymphocytes, and c-reactive protein over 2 weeks. This pilot study shows that ReDS can track changes in lung involvement according to the severity of COVID-19. Further studies to detect early clinical deterioration are needed.