Decreased Levels of Spleen Tissue CD4+CD25+Foxp3+ Regulatory T Lymphocytes in Mice Exposed to Berberine

The effects of isoquinoline alkaloid berberine (BER) on spleen tissue CD4+CD25+Foxp3+ regulatory T (Treg) cells were evaluated in BALB/c mice. Here, BER was administered daily by intraperitoneal injection at doses of 5 mg/kg and 10 mg/kg for 14 days. Following the exposure, mice spleen cellularities...

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Bibliographic Details
Main Authors: Gholamreza Karimi, Mahmoud Mahmoudi, Mahdi Balali-Mood, Maryam Rahnama, Shahrzad Zamani Taghizadeh Rabe, Nafiseh Tabasi, Bamdad Riahi-Zanjani
Format: Article
Language:English
Published: Medical Association of Pharmacopuncture Institute 2017-04-01
Series:Journal of Acupuncture & Meridian Studies
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2005290116302060