UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production

UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production

Uncoupling protein 2 (UCP2), an anion transporter, modulates the production of mitochondrial reactive oxygen species (ROS) and plays an important role in protecting against cell apoptosis. However, the role of UCP2 in sepsis-associated AKI remains unclear. In the present study, we investigated the r...

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Bibliographic Details
Main Authors: Xiaoyi Zhong, Jin He, Xi Zhang, Chengsheng Li, Xiaofang Tian, Wenyu Xia, Hua Gan, Yunfeng Xia
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Uncoupling protein-2
AKI
ROS
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219300745

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