Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration.

Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration.

Junctional complexes between endothelial cells form a dynamic barrier that hinders passive diffusion of blood constituents into interstitial tissues. Remodelling of junctions is an essential process during leukocyte trafficking, vascular permeability, and angiogenesis. However, for many junctional p...

Full description

Bibliographic Details
Main Authors:	Katja B Kostelnik, Amy Barker, Christopher Schultz, Tom P Mitchell, Vinothini Rajeeve, Ian J White, Michel Aurrand-Lions, Sussan Nourshargh, Pedro Cutillas, Thomas D Nightingale
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-12-01
Series:	PLoS Biology
Online Access:	https://doi.org/10.1371/journal.pbio.3000554

Similar Items

JAM-C/Jam-C Expression Is Primarily Expressed in Mouse Hematopoietic Stem Cells
by: Elia Henry, et al.
Published: (2021-07-01)

Trafficking and Turnover in Neuronal Axons
by: Ashrafi, Ghazaleh
Published: (2014)

Murine Bone Marrow Niches from Hematopoietic Stem Cells to B Cells
by: Michel Aurrand-Lions, et al.
Published: (2018-08-01)

Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases
by: David Bradley, et al.
Published: (2021-01-01)

Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells
by: Nosheen Akhtar, et al.
Published: (2020-09-01)

Endothelial JAM-A Facilitates Reovirus Bloodstream Spread
by: Lai, Caroline Ming-Hwei
Published: (2013)

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus.
by: Lena Wyss, et al.
Published: (2012-01-01)

Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors
by: Marisa S Goo, et al.
Published: (2015-10-01)

Vascular Endothelial Galectins in Leukocyte Trafficking
by: Abbey Lightfoot, et al.
Published: (2021-06-01)

Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity
by: Martina Beyrau, et al.
Published: (2012-01-01)

Resolving Subcellular miRNA Trafficking and Turnover at Single-Molecule Resolution
by: Sethuramasundaram Pitchiaya, et al.
Published: (2017-04-01)

Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments
by: Sagi Barzilai, et al.
Published: (2017-01-01)

Expression and function of junctional adhesion molecule (JAM)-C in murine endothelial cells and peripheral nerves : a study using JAM-C deficient mice
by: Scheiermann, Christoph
Published: (2008)

Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin
by: Sora Lee, et al.
Published: (2017-11-01)

Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
by: Daniel Kummer, et al.
Published: (2018-03-01)

Endothelial vegfrl expression and trafficking under normoxic and hypoxic conditions
by: Ulyatt, Clare Louise
Published: (2010)

Regulation of VEGFR1 localisation and trafficking in human endothelial cells
by: Mittar, Shweta
Published: (2006)

CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis
by: Mohammad Golam Sabbir
Published: (2020-05-01)

Culture Jammed
by: Andreas Oberprantacher
Published: (2011-07-01)

JAMS Flyer
by: Shafiur Rahman
Published: (2020-04-01)

Sex Trafficking 101: What are the Outcomes of Sex Trafficking Training?
by: Capparelli, Amy L.
Published: (2019)

Jamming decision under condition of incomplete jamming rule library
by: Qiang Xing, et al.
Published: (2019-10-01)

Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma
by: Thomas Simon, et al.
Published: (2018-08-01)

“Victims of Trafficking”: The Feminisation of Poverty and Migration in the Gendered Narratives of Human Trafficking
by: Amy M. Russell
Published: (2014-10-01)

The role of glutamate transporters and the scaffolding protein IQGAP1 in the regulation of AMPA receptor trafficking and turnover
by: Jarzylo, Larissa A.
Published: (2015)

T Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity
by: Christopher Vincent Carman, et al.
Published: (2015-11-01)

Jam Sessions as Rites of Passage: An Ethnography of Jazz Jams in Phoenix, AZ
Published: (2019)

jamSheets: Thin Interfaces with Tunable Stiffness Enabled by Layer Jamming
by: Ou, Jifei, et al.
Published: (2014)

Investigating the effects of Zeta Inhibitory Peptide on AMPAR trafficking
by: Barker, Ellen
Published: (2012)

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.
by: Amandine Cartier-Michaud, et al.
Published: (2017-06-01)

Positioning of jamming aircraft using the integrated refractive effects prediction system.
by: White, Thomas Wilson
Published: (2012)

Jamming of GNNS signals
by: Pokrajac Ivan, et al.
Published: (2018-01-01)

Khwaam Jam : Memory
by: Crane, Keith Lee
Published: (2009)

Digital communications jamming.
by: Sen, Cem.
Published: (2013)

Robotic granular jamming
by: Jiang, Allen
Published: (2014)

Poems by jam ismail
by: jam ismail
Published: (2014-12-01)

JamSys: Coverage Optimization of a Microphone Jamming System Based on Ultrasounds
by: Hao Shen, et al.
Published: (2019-01-01)

Spreadable Jams: Implementing Social Scholarship through Remodeled Game Jam Paradigms
by: Jon Saklofske
Published: (2019-02-01)

Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells
by: Juliete A. F. Silva, et al.
Published: (2021-08-01)

A Mechanism for VEGFR2 Trafficking, Signalling and Degradation in Human Endothelial Cells
by: Jopling, Helen Mary
Published: (2008)

Cannot write session to /tmp/vufind_sessions/sess_mieqtomis2m9sti1ajgbi3n3q1