Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation.

Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation.

Improper regulation of B cell responses leads to excessive production of antibodies and contributes to the development of autoimmune disease. T helper 17 (Th17) cells also drive the development of autoimmune disease, but the role of B cells in shaping Th17 cell-mediated immune responses, as well as...

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Bibliographic Details
Main Authors: Andrew C Melton, Jennifer Melrose, Liisa Alajoki, Sylvie Privat, Hannah Cho, Naomi Brown, Ana Marija Plavec, Dat Nguyen, Elijah D Johnston, Jian Yang, Mark A Polokoff, Ivan Plavec, Ellen L Berg, Alison O'Mahony
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3591360?pdf=render

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