Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release

CeF3:Tb3+ nanoparticles were successfully prepared by a polyol process using diethylene glycol (DEG) as solvent. After being coated with dense silica, these CeF3:Tb3+ nanoparticles can be coated with mesoporous silica using nonionic triblock copolymer EO20PO70EO20 (P 123) as structure-directing agen...

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Main Authors: Deyan Kong, Piaoping Yang, Zhenling Wang, Ping Chai, Shanshan Huang, Hongzhou Lian, Jun Lin
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2008/312792
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spelling doaj-b299ab59b60e47cb8e9f12f26900aaad2020-11-24T22:25:17ZengHindawi LimitedJournal of Nanomaterials1687-41101687-41292008-01-01200810.1155/2008/312792312792Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug ReleaseDeyan Kong0Piaoping Yang1Zhenling Wang2Ping Chai3Shanshan Huang4Hongzhou Lian5Jun Lin6State Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaState Key Laboratory of Application of Rare Earth Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaCeF3:Tb3+ nanoparticles were successfully prepared by a polyol process using diethylene glycol (DEG) as solvent. After being coated with dense silica, these CeF3:Tb3+ nanoparticles can be coated with mesoporous silica using nonionic triblock copolymer EO20PO70EO20 (P 123) as structure-directing agent. The composite can load ibuprofen and release the drug in the PBS. The composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen absorption/desorption isotherms, fluorescence spectra, and UV/Vis absorption spectra, respectively. The composite particles have considerable large pore volume and large surface area. In addition, the composite still emits strong green fluorescence (Tb3+) and can be used as fluorescent probes in drug delivery system.http://dx.doi.org/10.1155/2008/312792
collection DOAJ
language English
format Article
sources DOAJ
author Deyan Kong
Piaoping Yang
Zhenling Wang
Ping Chai
Shanshan Huang
Hongzhou Lian
Jun Lin
spellingShingle Deyan Kong
Piaoping Yang
Zhenling Wang
Ping Chai
Shanshan Huang
Hongzhou Lian
Jun Lin
Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
Journal of Nanomaterials
author_facet Deyan Kong
Piaoping Yang
Zhenling Wang
Ping Chai
Shanshan Huang
Hongzhou Lian
Jun Lin
author_sort Deyan Kong
title Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
title_short Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
title_full Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
title_fullStr Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
title_full_unstemmed Mesoporous Silica Coated CeF3:Tb3+ Particles for Drug Release
title_sort mesoporous silica coated cef3:tb3+ particles for drug release
publisher Hindawi Limited
series Journal of Nanomaterials
issn 1687-4110
1687-4129
publishDate 2008-01-01
description CeF3:Tb3+ nanoparticles were successfully prepared by a polyol process using diethylene glycol (DEG) as solvent. After being coated with dense silica, these CeF3:Tb3+ nanoparticles can be coated with mesoporous silica using nonionic triblock copolymer EO20PO70EO20 (P 123) as structure-directing agent. The composite can load ibuprofen and release the drug in the PBS. The composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen absorption/desorption isotherms, fluorescence spectra, and UV/Vis absorption spectra, respectively. The composite particles have considerable large pore volume and large surface area. In addition, the composite still emits strong green fluorescence (Tb3+) and can be used as fluorescent probes in drug delivery system.
url http://dx.doi.org/10.1155/2008/312792
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AT pingchai mesoporoussilicacoatedcef3tb3particlesfordrugrelease
AT shanshanhuang mesoporoussilicacoatedcef3tb3particlesfordrugrelease
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