Prediction of Long-Term Treatment Response to Selective Serotonin Reuptake Inhibitors (SSRIs) Using Scalp and Source Loudness Dependence of Auditory Evoked Potentials (LDAEP) Analysis in Patients with Major Depressive Disorder

Prediction of Long-Term Treatment Response to Selective Serotonin Reuptake Inhibitors (SSRIs) Using Scalp and Source Loudness Dependence of Auditory Evoked Potentials (LDAEP) Analysis in Patients with Major Depressive Disorder

Background: Animal and clinical studies have demonstrated that the loudness dependence of auditory evoked potentials (LDAEP) is inversely related to central serotonergic activity, with a high LDAEP reflecting weak serotonergic neurotransmission and vice versa, though the findings in humans have been...

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Bibliographic Details
Main Authors: Bun-Hee Lee, Young-Min Park, Seung-Hwan Lee, Miseon Shim
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
antidepressants
loudness dependence of auditory evoked potentials (LDAEP)
standardized low resolution brain electromagnetic tomography (sLORETA)
major depressive disorder
response
serotonin
Online Access:http://www.mdpi.com/1422-0067/16/3/6251

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