Rosiglitasone and ROCK Inhibitors Modulate Fibrogenetic Changes in TGF-β2 Treated Human Conjunctival Fibroblasts (HconF) in Different Manners

Rosiglitasone and ROCK Inhibitors Modulate Fibrogenetic Changes in TGF-β2 Treated Human Conjunctival Fibroblasts (HconF) in Different Manners

Purpose: The effects of Rho-associated coiled-coil containing protein kinase (ROCK) 1 and 2 inhibitor, ripasudil hydrochloride hydrate (Rip), ROCK2 inhibitor, KD025 or rosiglitazone (Rosi) on two-dimension (2D) and three-dimension (3D) cultured human conjunctival fibroblasts (HconF) treated by trans...

Full description

Bibliographic Details
Main Authors: Yuika Oouchi, Megumi Watanabe, Yosuke Ida, Hiroshi Ohguro, Fumihito Hikage
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
TGFβ2
human conjunctival fibroblast
ROCK inhibitor
3D culture
ripasudil
KD025
Online Access:https://www.mdpi.com/1422-0067/22/14/7335

Internet

https://www.mdpi.com/1422-0067/22/14/7335

Similar Items