Evolution of Alu Elements toward Enhancers

Summary: The human genome contains approximately one million Alu repetitive elements comprising 10% of the genome, yet their functions are not well understood. Here, we show that Alu elements resemble enhancers. Alu elements are bound by two well-phased nucleosomes that contain histones bearing mark...

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Bibliographic Details
Main Authors: Ming Su, Dali Han, Jerome Boyd-Kirkup, Xiaoming Yu, Jing-Dong J. Han
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714001892