Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam
Abstract New antigens deriving from -lloyl and -llanyl, major and minor determinants, respectively, were produced for β-lactam antibiotics cefuroxime, cefotaxime, ceftriaxone, meropenem and aztreonam. Twenty β-lactam antigens were produced using human serum albumin and histone H1 as carrier proteins...
Main Authors: | Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-73109-w |
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