Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam

Abstract New antigens deriving from -lloyl and -llanyl, major and minor determinants, respectively, were produced for β-lactam antibiotics cefuroxime, cefotaxime, ceftriaxone, meropenem and aztreonam. Twenty β-lactam antigens were produced using human serum albumin and histone H1 as carrier proteins...

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Bibliographic Details
Main Authors: Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-73109-w